RAS Guanyl Nucleotide-Releasing Protein 2 (RASGRP2) Antibody
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Catalogue No: abx026639
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US$326.25
(Size: 80 µl)
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Datasheet SDS
The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Three alternatively spliced transcript variants encoding the same protein have been found for this gene.
Research Articles on RAS Guanyl Nucleotide-Releasing Protein 2 (RASGRP2)
| Target | RAS Guanyl Nucleotide-Releasing Protein 2 (RASGRP2) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50, IF/ICC: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 7-34 amino acids from the N-terminal region of human RASGRP2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q7LDG7 (UniProt, ExPASy) |
| UniProt Secondary AC | A6NDC7, O00538, Q9UL65 |
| UniProt Entry Name | GRP2_HUMAN |
| Gene Symbol | RASGRP2 |
| KEGG | hsa:10235 |
| String | 9606.ENSP00000338864 |
| Molecular Weight | Calculated MW: 69.2 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Rat and Cow RASGRP2. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |