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Ras Association Domain-Containing Protein 1 (RASSF1) Antibody

Catalogue No: abx001115
Price: £120.00
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Ras Association Domain-Containing Protein 1 (RASSF1) Antibody

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RASSF1 Antibody is a Rabbit Polyclonal antibody against RASSF1. This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Several alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, May 2011].

Target RASSF1
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human RASSF1.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q9NS23 (UniProt, ExPASy)
UniProt Entry Name RASF1_HUMAN
Gene Symbol RASSF1
GeneID 11186
String 9606.ENSP00000349547
Molecular Weight Calculated MW: 8 kDa, 9 kDa, 16 kDa, 21 kDa, 31 kDa, 38 kDa, 39 kDa
Observed MW: 39 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Ras Association Domain-Containing Protein 1 (RASSF1) Antibody

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