Ras Association Domain-Containing Protein 1 (RASSF1) Antibody

RASSF1 Antibody is a Rabbit Polyclonal antibody against RASSF1. This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Several alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, May 2011].

Target	Ras Association Domain-Containing Protein 1 (RASSF1)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 101-340 of human RASSF1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9NS23 (UniProt, ExPASy)
UniProt Entry Name	RASF1_HUMAN
Gene Symbol	RASSF1
GeneID	11186
NCBI Accession	NP_009113.3
String	9606.ENSP00000349547
Molecular Weight	Calculated MW: 39 kDa Observed MW: 39 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Ras Association Domain-Containing Protein 1 (RASSF1)

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