Histone-Binding Protein RBBP4 (RBBP4) Antibody

RBBP4 Antibody is a Rabbit Polyclonal antibody against RBBP4. This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. It is present in protein complexes involved in histone acetylation and chromatin assembly. It is part of the Mi-2 complex which has been implicated in chromatin remodeling and transcriptional repression associated with histone deacetylation. This encoded protein is also part of co-repressor complexes, which is an integral component of transcriptional silencing. It is found among several cellular proteins that bind directly to retinoblastoma protein to regulate cell proliferation. This protein also seems to be involved in transcriptional repression of E2F-responsive genes. Three transcript variants encoding different isoforms have been found for this gene.

Target	Histone-Binding Protein RBBP4 (RBBP4)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IF/ICC, IP
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200, IP: 0.5-4 µg/200-400 µg whole cell extracts, ChIP: 5 µg/10-15 µg Chromatin. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-425 of human RBBP4.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q09028 (UniProt, ExPASy)
UniProt Secondary AC	B2R6G9, B4DRH0, D3DPQ3, P31149, Q53H02, Q96BV9
UniProt Entry Name	RBBP4_HUMAN
Gene Symbol	RBBP4
GeneID	5928
NCBI Accession	NP_005601.1
KEGG	hsa:5928
String	9606.ENSP00000362592
Molecular Weight	Calculated MW: 48 kDa Observed MW: 55 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Histone-Binding Protein RBBP4 (RBBP4)

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