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Receptor-Type Tyrosine-Protein Phosphatase C / CD45 (PTPRC) Antibody
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Catalogue No: abx239868
Price:
US$406.00
(Size: 100 µg)
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Receptor-Type Tyrosine-Protein Phosphatase C / CD45 (PTPRC) Antibody is a Mouse Monoclonal antibody for the detection of CD45. CD45, also known as leukocyte common antigen (LCA), B220, and T200, is a 180-240 kDa single chain type I membrane glycoprotein. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes and platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation.
Research Articles on Receptor-Type Tyrosine-Protein Phosphatase C / CD45 (PTPRC)
| Target | Receptor-Type Tyrosine-Protein Phosphatase C / CD45 (PTPRC) |
| Clonality | Monoclonal |
| Reactivity | Human, Pig |
| Tested Applications | ELISA, WB, IHC, FCM |
| Host | Mouse |
| Recommended dilutions | WB: 1/1000 - 1/10000, IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | protein tyrosine phosphatase, receptor type, C |
| Isotype | IgG2a |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by Protein A and Protein G affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Validity | 12 months. |
| UniProt Primary AC | P08575 (UniProt, ExPASy) |
| UniProt Secondary AC | A0A0A0MT22, A8K7W6, Q16614, Q9H0Y6, X6R433 |
| UniProt Entry Name | PTPRC_HUMAN |
| Gene Symbol | PTPRC |
| GeneID | 5788 |
| OMIM | 126200 |
| HGNC | 9666 |
| KEGG | hsa:5788 |
| Ensembl | ENSG00000081237 |
| String | 9606.ENSP00000411355 |
| Molecular Weight | Observed MW: 180-220 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |