Receptor-Type Tyrosine-Protein Phosphatase C / CD45 (PTPRC) Antibody

Receptor-Type Tyrosine-Protein Phosphatase C / CD45 (PTPRC) Antibody is a Mouse Monoclonal antibody for the detection of CD45.

CD45, also known as leukocyte common antigen (LCA), B220, and T200, is a 180-240 kDa single chain type I membrane glycoprotein. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes and platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation.

Target	Receptor-Type Tyrosine-Protein Phosphatase C / CD45 (PTPRC)
Clonality	Monoclonal
Reactivity	Human, Pig
Tested Applications	ELISA, WB, IHC, FCM
Host	Mouse
Recommended dilutions	WB: 1/1000 - 1/10000, IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	protein tyrosine phosphatase, receptor type, C
Isotype	IgG2a
Form	Liquid
Purity	≥ 95% (SDS-PAGE)
Purification	Purified by Protein A and Protein G affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity	12 months.
UniProt Primary AC	P08575 (UniProt, ExPASy)
UniProt Secondary AC	A0A0A0MT22, A8K7W6, Q16614, Q9H0Y6, X6R433
UniProt Entry Name	PTPRC_HUMAN
Gene Symbol	PTPRC
GeneID	5788
OMIM	126200
HGNC	9666
KEGG	hsa:5788
Ensembl	ENSG00000081237
String	9606.ENSP00000411355
Molecular Weight	Observed MW: 180-220 kDa
Buffer	PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration	2 mg/ml
Availability	Shipped within 5-12 working days.
Note	This product is for research use only.

Research Articles on Receptor-Type Tyrosine-Protein Phosphatase C / CD45 (PTPRC)

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