Proto-Oncogene C-Rel (REL) Antibody

REL Antibody is a Rabbit Polyclonal antibody against REL. This gene encodes a protein that belongs to the Rel homology domain/immunoglobulin-like fold, plexin, transcription factor (RHD/IPT) family. Members of this family regulate genes involved in apoptosis, inflammation, the immune response, and oncogenic processes. This proto-oncogene plays a role in the survival and proliferation of B lymphocytes. Mutation or amplification of this gene is associated with B-cell lymphomas, including Hodgkin's lymphoma. Single nucleotide polymorphisms in this gene are associated with susceptibility to ulcerative colitis and rheumatoid arthritis. Alternative splicing results in multiple transcript variants encoding different isoforms.

Target	Proto-Oncogene C-Rel (REL)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human REL.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q04864 (UniProt, ExPASy)
UniProt Secondary AC	Q17RU2, Q2PNZ7, Q6LDY0
UniProt Entry Name	REL_HUMAN
Gene Symbol	REL
GeneID	5966
NCBI Accession	NP_002899.1
KEGG	hsa:5966
String	9606.ENSP00000295025
Molecular Weight	Calculated MW: 69 kDa Observed MW: 78 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Proto-Oncogene C-Rel (REL)

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