Replication Factor C Subunit 3 (RFC3) Antibody

RFC3 Antibody is a Rabbit Polyclonal antibody against RFC3. The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kDa. This gene encodes the 38 kDa subunit. This subunit is essential for the interaction between the 140 kDa subunit and the core complex that consists of the 36, 37, and 40 kDa subunits. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Target	Replication Factor C Subunit 3 (RFC3)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human RFC3.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P40938 (UniProt, ExPASy)
UniProt Secondary AC	C9JU95, O15252, Q5W0E8
UniProt Entry Name	RFC3_HUMAN
Gene Symbol	RFC3
GeneID	5983
NCBI Accession	NP_002906.1
KEGG	hsa:5983
String	9606.ENSP00000369411
Molecular Weight	Calculated MW: 41 kDa Observed MW: 41 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Replication Factor C Subunit 3 (RFC3)

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