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Rho-Related GTP-Binding Protein RhoC (RHOC) Antibody

Catalogue No: abx000985
Price: £160.00
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Rho-Related GTP-Binding Protein RhoC (RHOC) Antibody Rho-Related GTP-Binding Protein RhoC (RHOC) Antibody Rho-Related GTP-Binding Protein RhoC (RHOC) Antibody

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RHOC Antibody is a Rabbit Polyclonal antibody against RHOC. This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Target RHOC
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human RHOC.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P08134 (UniProt, ExPASy)
UniProt Secondary AC B3KSW1, Q6ICN3
UniProt Entry Name RHOC_HUMAN
Gene Symbol RHOC
GeneID 389
KEGG hsa:389
String 9606.ENSP00000285735
Molecular Weight Calculated MW: 22 kDa
Observed MW: 22 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Rho-Related GTP-Binding Protein RhoC (RHOC) Antibody

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