Ribonuclease H2 Subunit B (RNASEH2B) Antibody

RNASEH2B Antibody is a Rabbit Polyclonal antibody against RNASEH2B. RNase H2 is composed of a single catalytic subunit (A) and two non-catalytic subunits (B and C) and specifically degrades the RNA of RNA:DNA hybrids. The protein encoded by this gene is the non-catalytic B subunit of RNase H2, which is thought to play a role in DNA replication. Multiple transcript variants encoding different isoforms have been found for this gene. Defects in this gene are a cause of Aicardi-Goutieres syndrome type 2 (AGS2).

Target	Ribonuclease H2 Subunit B (RNASEH2B)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human RNASEH2B.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q5TBB1 (UniProt, ExPASy)
UniProt Secondary AC	G3XAJ1, Q05DR2, Q6PK48, Q9HAF7
UniProt Entry Name	RNH2B_HUMAN
Gene Symbol	RNASEH2B
GeneID	79621
NCBI Accession	NP_078846.2
KEGG	hsa:79621
String	9606.ENSP00000337623
Molecular Weight	Calculated MW: 35 kDa Observed MW: 37 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Ribonuclease H2 Subunit B (RNASEH2B)

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