E3 Ubiquitin-Protein Ligase RNF128 (RNF128) Antibody

The protein encoded by this gene is a type I transmembrane protein that localizes to the endocytic pathway. This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity. Expression of this gene in retrovirally transduced T cell hybridoma significantly inhibits activation-induced IL2 and IL4 cytokine production. Induced expression of this gene was observed in anergic CD4 (+) T cells, which suggested a role in the induction of anergic phenotype. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Target	E3 Ubiquitin-Protein Ligase RNF128 (RNF128)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 115-143 amino acids from the Central region of human RNF128.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q8TEB7 (UniProt, ExPASy)
UniProt Secondary AC	A0PJI4, Q6PH80, Q6ZTJ8, Q96RF3, Q9H5E4
UniProt Entry Name	RN128_HUMAN
Gene Symbol	RNF128
KEGG	hsa:79589
String	9606.ENSP00000255499
Molecular Weight	Calculated MW: 46.5 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Cow RNF128.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on E3 Ubiquitin-Protein Ligase RNF128 (RNF128)

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