Receptor Tyrosine Kinase Like Orphan Receptor 1 (ROR1) Antibody

Catalogue No: abx002361
Price: £120.00
(Size: 20 µl)
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ROR1 Antibody is a Rabbit Polyclonal antibody against ROR1. This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms.

Target ROR1
Clonality Polyclonal
Reactivity Human
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human ROR1.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q01973 (UniProt, ExPASy)
UniProt Secondary AC Q5VVX6, Q66K77, Q92776
UniProt Entry Name ROR1_HUMAN
Gene Symbol ROR1
GeneID 4919
KEGG hsa:4919
String 9606.ENSP00000360120
Molecular Weight Calculated MW: 42 kDa, 43 kDa, 104 kDa
Observed MW: 120 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Receptor Tyrosine Kinase Like Orphan Receptor 1 (ROR1) Antibody

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