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Receptor Tyrosine Kinase Like Orphan Receptor 1 (ROR1) Antibody
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Catalogue No: abx002361
Price:
£120.00
(Size: 20 µl)
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ROR1 Antibody is a Rabbit Polyclonal antibody against ROR1. This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms.
Research Articles on ROR1
| Target | ROR1 |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant protein of human ROR1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q01973 (UniProt, ExPASy) |
| UniProt Secondary AC | Q5VVX6, Q66K77, Q92776 |
| UniProt Entry Name | ROR1_HUMAN |
| Gene Symbol | ROR1 |
| GeneID | 4919 |
| KEGG | hsa:4919 |
| String | 9606.ENSP00000360120 |
| Molecular Weight | Calculated MW: 42 kDa, 43 kDa, 104 kDa Observed MW: 120 kDa |
| Buffer | PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.5 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |
