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X-Linked Retinitis Pigmentosa GTPase Regulator (RPGR) Antibody

Catalogue No: abx001524
Price: £120.00
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X-Linked Retinitis Pigmentosa GTPase Regulator (RPGR) Antibody

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RPGR Antibody is a Rabbit Polyclonal antibody against RPGR. This gene encodes a protein with a series of six RCC1-like domains (RLDs), characteristic of the highly conserved guanine nucleotide exchange factors. The encoded protein is found in the Golgi body and interacts with RPGRIP1. This protein localizes to the outer segment of rod photoreceptors and is essential for their viability. Mutations in this gene have been associated with X-linked retinitis pigmentosa (XLRP). Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length natures of only some have been determined. [provided by RefSeq, Dec 2008].

Target RPGR
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human RPGR.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q92834 (UniProt, ExPASy)
UniProt Entry Name RPGR_HUMAN
Gene Symbol RPGR
GeneID 6103
KEGG hsa:6103
String 9606.ENSP00000367766
Molecular Weight Calculated MW: 52 kDa, 70 kDa, 83 kDa, 90 kDa, 113 kDa, 127 kDa
Observed MW: 85 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration 1.01 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on X-Linked Retinitis Pigmentosa GTPase Regulator (RPGR) Antibody

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