Large Ribosomal Subunit Protein P1 (RPLP1) Antibody
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Catalogue No: abx005158
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US$217.50
(Size: 20 µl)
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Datasheet SDS
Large Ribosomal Subunit Protein P1 (RPLP1) Antibody is a Rabbit Polyclonal antibody against Large Ribosomal Subunit Protein P1 (RPLP1). Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. The RPLP1 gene encodes a ribosomal phosphoprotein that is a component of the 60S subunit. The protein, which is a functional equivalent of the E. coli L7/L12 ribosomal protein, belongs to the L12P family of ribosomal proteins. It plays an important role in the elongation step of protein synthesis. Unlike most ribosomal proteins, which are basic, the encoded protein is acidic and it's C-terminal end is nearly identical to the C-terminal ends of the ribosomal phosphoproteins P0 and P2. The P1 protein can interact with P0 and P2 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer. The protein is located in the cytoplasm. Two alternatively spliced transcript variants that encode different proteins have been observed. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Research Articles on Large Ribosomal Subunit Protein P1 (RPLP1)
| Target | Large Ribosomal Subunit Protein P1 (RPLP1) |
| Research Area | Developmental Science |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat, Zebrafish |
| Tested Applications | ELISA, WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant protein corresponding to Large Ribosomal Subunit Protein P1 (RPLP1). The exact sequence is proprietary. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P05386 (UniProt, ExPASy) |
| UniProt Secondary AC | A6NIB2 |
| UniProt Entry Name | RLA1_HUMAN |
| Gene Symbol | RPLP1 |
| GeneID | 6176 |
| NCBI Accession | NP_000994.1 |
| KEGG | hsa:6176 |
| String | 9606.ENSP00000346037 |
| Molecular Weight | Calculated MW: 12 kDa Observed MW: 17 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 7.52 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |