40S Ribosomal Protein S3 (RPS3) Antibody

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Catalogue No: abx001973
Price: US$203.00
(Size: 20 µl)

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Datasheet SDS
RPS3 Antibody is a Rabbit Polyclonal antibody against RPS3. Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit, where it forms part of the domain where translation is initiated. The protein belongs to the S3P family of ribosomal proteins. Studies of the mouse and rat proteins have demonstrated that the protein has an extraribosomal role as an endonuclease involved in the repair of UV-induced DNA damage. The protein appears to be located in both the cytoplasm and nucleus but not in the nucleolus. Higher levels of expression of this gene in colon adenocarcinomas and adenomatous polyps compared to adjacent normal colonic mucosa have been observed. This gene is co-transcribed with the small nucleolar RNA genes U15A and U15B, which are located in its first and fifth introns, respectively. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Target 40S Ribosomal Protein S3 (RPS3)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-243 of human RPS3.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P23396 (UniProt, ExPASy)
UniProt Secondary AC B2R7N5, J3KN86, Q498B5, Q8NI95
UniProt Entry Name RS3_HUMAN
Gene Symbol RPS3
GeneID 6188
OMIM 600454
NCBI Accession NP_000996.2
HGNC 10420
KEGG hsa:6188
Ensembl ENSG00000149273
String 9606.ENSP00000278572
Molecular Weight Calculated MW: 27 kDa
Observed MW: 33 kDa
Buffer PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration > 0.2 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on 40S Ribosomal Protein S3 (RPS3)


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