Ribosomal Protein S6 Kinase Beta 1 (RPS6KB1) Antibody

RPS6KB1 Antibody is a Rabbit Polyclonal antibody against RPS6KB1. This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17.

Target	Ribosomal Protein S6 Kinase Beta 1 (RPS6KB1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 421-520 of human p70 S6 Kinase 1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P23443 (UniProt, ExPASy)
UniProt Secondary AC	B2R779, B4DLT4, B4DTG1, E7ESB8, F6UYM1, Q7Z721
UniProt Entry Name	KS6B1_HUMAN
Gene Symbol	RPS6KB1
GeneID	6198
NCBI Accession	NP_003152.1
KEGG	hsa:6198
String	9606.ENSP00000225577
Molecular Weight	Calculated MW: 59 kDa Observed MW: 70 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Ribosomal Protein S6 Kinase Beta 1 (RPS6KB1)

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