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Ribonucleoside-Diphosphate Reductase Large Subunit (RRM1) Antibody

Catalogue No: abx001066
Price: £120.00
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Ribonucleoside-Diphosphate Reductase Large Subunit (RRM1) Antibody Ribonucleoside-Diphosphate Reductase Large Subunit (RRM1) Antibody

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RRM1 Antibody is a Rabbit Polyclonal antibody against RRM1. This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region.

Target RRM1
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human RRM1.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P23921 (UniProt, ExPASy)
UniProt Secondary AC Q9UNN2
UniProt Entry Name RIR1_HUMAN
Gene Symbol RRM1
GeneID 6240
String 9606.ENSP00000300738
Molecular Weight Calculated MW: 90 kDa
Observed MW: 100 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Ribonucleoside-Diphosphate Reductase Large Subunit (RRM1) Antibody

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