Runt Related Transcription Factor (RUNX1) Antibody

RUNX1 Antibody is a Rabbit Polyclonal antibody against RUNX1. Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene.

Target	Runt Related Transcription Factor (RUNX1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/700, IHC-P: 1/50 - 1/100, IF/ICC: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 171-260 of human RUNX1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q01196 (UniProt, ExPASy)
UniProt Entry Name	RUNX1_HUMAN
Gene Symbol	RUNX1
GeneID	861
NCBI Accession	NP_001001890.1
KEGG	hsa:861
String	9606.ENSP00000300305
Molecular Weight	Calculated MW: 49 kDa Observed MW: 55 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Runt Related Transcription Factor (RUNX1)

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