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Runt-Related Transcription Factor 2 (RUNX2) Antibody
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Catalogue No: abx002106
Price:
US$348.00
(Size: 60 µl)
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RUNX2 Antibody is a Rabbit Polyclonal antibody against RUNX2. This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing.
Research Articles on Runt-Related Transcription Factor 2 (RUNX2)
| Target | Runt-Related Transcription Factor 2 (RUNX2) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human RUNX2 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q13950 (UniProt, ExPASy) |
| UniProt Secondary AC | O14614, O14615, O95181 |
| UniProt Entry Name | RUNX2_HUMAN |
| Gene Symbol | RUNX2 |
| GeneID | 860 |
| NCBI Accession | NP_001019801.3 |
| KEGG | hsa:860 |
| String | 9606.ENSP00000360493 |
| Molecular Weight | Calculated MW: 54 kDa/55 kDa/56 kDa Observed MW: 70 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
