Runt Related Transcription Factor 3 (RUNX3) Antibody

This gene encodes a member of the runt domain-containing family of transcription factors.A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription.It also interacts with other transcription factors.It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer.Multiple transcript variants encoding different isoforms have been found for this gene.

Target	Runt Related Transcription Factor 3 (RUNX3)
Clonality	Monoclonal
Reactivity	Human, Mouse
Tested Applications	ELISA, IHC, IF/ICC, FCM
Host	Mouse
Recommended dilutions	ELISA: 1/10000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of human RUNX3 (AA:186-252) expressed in E. coli.
Isotype	IgG2b
Form	Liquid
Purification	Purified from ascites by Protein G chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
GeneID	864
Molecular Weight	44.4 kDa
Buffer	PBS, containing 0.05% sodium azide.
Concentration	1 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Runt Related Transcription Factor 3 (RUNX3)

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