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Runt Related Transcription Factor 3 (RUNX3) Antibody
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Catalogue No: abx015982
Price:
US$427.75
(Size: 100 µl)
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Datasheet SDS
This gene encodes a member of the runt domain-containing family of transcription factors.A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription.It also interacts with other transcription factors.It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer.Multiple transcript variants encoding different isoforms have been found for this gene.
Research Articles on Runt Related Transcription Factor 3 (RUNX3)
| Target | Runt Related Transcription Factor 3 (RUNX3) |
| Research Area | Signaling Pathways, Drug Targets, Neurodegenerative, Actin Dynamics Signaling Pathway |
| Clonality | Monoclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, IHC, IF/ICC, FCM |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human RUNX3 (AA:186-252) expressed in E. coli. |
| Isotype | IgG2b |
| Form | Liquid |
| Purification | Purified from ascites by Protein G chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| GeneID | 864 |
| Molecular Weight | 44.4 kDa |
| Buffer | PBS, containing 0.05% sodium azide. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |