Menu

Ryanodine Receptor 2 (RYR2) Antibody

Catalogue No: abx000677
Price: £95.00
Reviews: 0 reviews
(0 reviews)

Click on the image to see the image legend

Ryanodine Receptor 2 (RYR2) Antibody Ryanodine Receptor 2 (RYR2) Antibody Ryanodine Receptor 2 (RYR2) Antibody

Available Options

* Size:




RYR2 Antibody is a Rabbit Polyclonal antibody against RYR2. RYR2 belongs to the ryanodine receptor family. RYR2 provides communication between transverse-tubules and sarcoplasmic reticulum. Contraction of cardiac muscle is triggered by release of calcium ions from SR following depolarization of T-tubules. Defects in RYR2 are the cause of familial arrhythmogenic right ventricular dysplasia type 2 (ARVD2) which known as arrhythmogenic right ventricular cardiomyopathy 2 (ARVC2). Defects in RYR2 are the cause of catecholaminergic polymorphic ventricular tachycardia type 1 (CPVT1) which known as stress-induced polymorphic ventricular tachycardia (VTSIP). This gene encodes a ryanodine receptor found in cardiac muscle sarcoplasmic reticulum. The encoded protein is one of the components of a calcium channel, composed of a tetramer of the ryanodine receptor proteins and a tetramer of FK506 binding protein 1B proteins, that supplies calcium to cardiac muscle. Mutations in this gene are associated with stress-induced polymorphic ventricular tachycardia and arrhythmogenic right ventricular dysplasia. [provided by RefSeq, Jul 2008].

Target RYR2
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Tested Applications WB, IHC
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Immunogen A synthetic peptide of human RYR2.
Purification Affinity purified.
Form Liquid
Isotype IgG
Conjugation Unconjugated
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Molecular Weight Calculated MW: 564 kDa, 565 kDa
Observed MW: 500 kDa
Swiss Prot Q92736
GeneID 6262
Gene Symbol RYR2
Concentration > 1 mg/ml
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
UNSPSC Code 12352203
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Ryanodine Receptor 2 (RYR2) Antibody

Write a review

Your Name
Your Email Address
PMID
DOI
Type
Your Review

Note: HTML is not translated!

Rating Bad Good


Tags:
(Click to show)