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S100BB Antibody
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Catalogue No: abx019328
Price:
US$841.00
(Size: 1 mg)
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Datasheet SDS
S100BB Antibody is a Mouse Monoclonal antibody against Human S100BB. For a sandwich immunoassay, it is recommended to use one of the following pairs:
Capture antibody: abx019328 (this product)
Detection antibody: abx019329 S100B (S100 calcium binding protein B) is a glial-derived protein that is a well-established biomarker for severity of neurological injury and prognosis for recovery. It functions as a neurotrophic factor and neuronal survival protein during development of the central nervous system. S100B is glial-specific and is expressed at high levels in brain primarily by a subtype of mature astrocytes that surround blood vessels and by NG2-expressing cells. The increased S100B in the brain can be detrimental and may augment pathogenic responses to injury by accelerating neuroinflammatory processes. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.
Research Articles on S100BB
Capture antibody: abx019328 (this product)
Detection antibody: abx019329 S100B (S100 calcium binding protein B) is a glial-derived protein that is a well-established biomarker for severity of neurological injury and prognosis for recovery. It functions as a neurotrophic factor and neuronal survival protein during development of the central nervous system. S100B is glial-specific and is expressed at high levels in brain primarily by a subtype of mature astrocytes that surround blood vessels and by NG2-expressing cells. The increased S100B in the brain can be detrimental and may augment pathogenic responses to injury by accelerating neuroinflammatory processes. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.
| Target | S100BB |
| Clonality | Monoclonal |
| Clone | X565 |
| Reactivity | Human |
| Tested Applications | ELISA, LF |
| Host | Mouse |
| Recommended dilutions | Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Form | Liquid |
| Purity | > 90% (HPLC and SDS-PAGE) |
| Purification | Purified from Mouse ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P04271 (UniProt, ExPASy) |
| UniProt Secondary AC | D3DSN6 |
| UniProt Entry Name | S100B_HUMAN |
| GeneID | 6285 |
| OMIM | 176990 |
| KEGG | hsa:6285 |
| String | 9606.ENSP00000291700 |
| Buffer | 0.01 M PBS, pH 7.4 ± 0.2. Does not contain preservatives. |
| Concentration | 1.08 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |