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SARS-CoV-2 Non-Structural Protein 3 Antibody
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Catalogue No: abx229990
Price:
US$406.00
(Size: 50 µl)
Orders to United States ship from United States
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Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2/COVID-19) NSP3 Antibody is a Rabbit Polyclonal antibody for the detection of SARS-CoV-2 NSP3. Responsible for the cleavages located at the N-terminus of the replicase polyprotein. In addition, PL-PRO possesses a deubiquitinating/deISGylating activity and processes both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains from cellular substrates. Participates together with nsp4 in the assembly of virally-induced cytoplasmic double-membrane vesicles necessary for viral replication. Antagonizes innate immune induction of type I interferon by blocking the phosphorylation, dimerization and subsequent nuclear translocation of host IRF3. Prevents also host NF-kappa-B signaling.
Research Articles on SARS-CoV-2 Non-Structural Protein 3
| Target | SARS-CoV-2 Non-Structural Protein 3 |
| Research Area | Infection Immunity |
| Clonality | Polyclonal |
| Reactivity | Virus |
| Tested Applications | ELISA |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1/4000 - 1/8000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant SARS-CoV-2 NSP3 (Glu1024-Gln1198) |
| Isotype | IgG |
| Form | Liquid |
| Storage | Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Buffer | PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | 0.31 mg/ml |
| Availability | Shipped within 5-15 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
| Directions for use | Centrifuge before opening to ensure complete recovery of vial contents. |
