SARS-CoV-2 NSP8 Antibody

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2/COVID-19) NSP8 Antibody is a Rabbit Polyclonal antibody for the detection of SARS-CoV-2 NSP8.

Cleavage by the viral main protease, 3CLpro results in generating the nsp8 protein, The nsp8 protein has been shown to associate with several other nsps and to colocalize with these nsps in cytoplasmic complexes that are important for viral RNA synthesis. It forms a hexadecamer with nsp7 (8 subunits of each) that may participate in viral replication by acting as a primase. Alternatively, may synthesize substantially longer products than oligonucleotide primers. Nsp8 was shown to have RNA-dependent RNA polymerase (RdRp) activity that could be involved in producing primers utilized by nsp12 which is normally accepted to be the RdRp for SARS-CoV.

Target	SARS-CoV-2
Clonality	Polyclonal
Reactivity	Virus
Tested Applications	ELISA
Host	Rabbit
Recommended dilutions	ELISA: 1/4000 - 1/8000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant SARS-CoV-2 NSP8 (A3943-Q4118)
Isotype	IgG
Form	Liquid
Storage	Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Buffer	PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol.
Concentration	0.29 mg/ml
Availability	Shipped within 5-15 working days.
Note	This product is for research use only.
Directions for use	Centrifuge before opening to ensure complete recovery of vial contents.

Research Articles on SARS-CoV-2

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