SARS-CoV-2 S1 Protein Antibody

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2/COVID-19) S1 Protein Antibody is a Mouse Monoclonal antibody for the detection of SARS-CoV-2 S1.

The SARS-CoV-2 Spike Protein (S protein) is a viral protein that allows the entry of SARS-CoV-2 into human cells. The protein forms trimers on the viral capsid and binds to human Angiotensin Converting Enzyme 2 (ACE2) located on the cell surface. The protein has a cleavage site between the S1 and S2 subunits that is targeted by the human enzyme Furin, and it may also cause the development of a syncytium (cell fusion). Antibodies to S protein can prevent viral entry as well as target the virus for further immune action.

Target	SARS-CoV-2 Spike Glycoprotein
Research Area	Infection Immunity
Clonality	Monoclonal
Clone	S317
Reactivity	Virus
Tested Applications	ELISA, WB, IHC
Host	Mouse
Recommended dilutions	ELISA: 1/4000 - 1/8000, WB: 1/2000 - 1/8000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant SARS-CoV-2 S Protein (Asn 679-Phe 833) expressed in E .coli.
Isotype	IgG1
Form	Liquid
Purity	> 95% (SDS-PAGE)
Purification	Purified from cell culture supernatant by Protein A/G affinity chromatography.
Storage	Store at 4 °C if the entire vial will be used within 1-2 weeks. For long-term storage, aliquot and store at -20 °C or -80 °C. Avoid repeated freeze-thaw cycles.
UniProt Primary AC	P0DTC2 (UniProt, ExPASy)
Buffer	0.01M PBS, pH 7.4, containing 50% glycerol, 0.05% Proclin 300.
Specificity	Recognizes SARS-CoV-2 (2019-nCoV).
Concentration	1.5 mg/ml
Availability	Shipped within 5-12 working days.
Note	THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Research Articles on SARS-CoV-2 Spike Glycoprotein

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