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SARS-CoV-2 Spike S2 Antibody
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Catalogue No: abx229986
Price:
US$406.00
(Size: 50 µl)
Orders to United States ship from United States
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Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2/COVID-19) S2 Antibody is a Rabbit Polyclonal antibody for the detection of SARS-CoV-2 S2. Mediates fusion of the virion and cellular membranes by acting as a class I viral fusion protein. Under the current model, the protein has at least three conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.
Research Articles on SARS-CoV-2 Spike S2
| Target | SARS-CoV-2 Spike S2 |
| Research Area | Infection Immunity |
| Clonality | Polyclonal |
| Reactivity | Virus |
| Tested Applications | ELISA |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1/4000 - 1/8000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant SARS-CoV-2 S2 Protein (Ser686-Pro1213) |
| Isotype | IgG |
| Form | Liquid |
| Storage | Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Buffer | PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | 0.30 mg/ml |
| Availability | Shipped within 5-15 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
| Directions for use | Centrifuge before opening to ensure complete recovery of vial contents. |
