SARS-CoV-2 Spike Neutralizing Antibody
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Catalogue No: abx229982
Price:
US$420.50
(Size: 50 µl)
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Datasheet SDS
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2/COVID-19) Spike Neutralizing Antibody is a Human monoclonal IgM antibody. The SARS-CoV-2 Spike Protein (S protein) is a viral protein that allows the entry of SARS-CoV-2 into human cells. The protein forms trimers on the viral capsid and binds to human Angiotensin Converting Enzyme 2 (ACE2) located on the cell surface. The protein has a cleavage site between the S1 and S2 subunits that is targeted by the human enzyme Furin, and it may also cause the development of a syncytium (cell fusion). Antibodies to S protein can prevent viral entry as well as target the virus for further immune action.
Research Articles on SARS-CoV-2 Spike
| Target | SARS-CoV-2 Spike |
| Research Area | Infection Immunity |
| Clonality | Monoclonal |
| Reactivity | Virus |
| Tested Applications | ELISA |
| Host | Human |
| Recommended dilutions | ELISA: 1/1000 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant SARS-CoV-2 S-trimer Protein |
| Isotype | IgM |
| Form | Liquid |
| Purification | Purified by ion column chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| Buffer | PBS, pH 7.4. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-15 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
| Directions for use | Centrifuge before opening to ensure complete recovery of vial contents. |
