Bebtelovimab

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2/COVID-19) Spike Protein RBD Neutralizing Antibody (Bebtelovimab) is a research grade Human Monoclonal Antibody biosimilar for the detection of SARS-CoV-2/COVID-19 Spike Protein.

The SARS-CoV-2 Spike Protein (S protein) is a viral protein that allows the entry of SARS-CoV-2 into human cells. The protein forms trimers on the viral capsid and binds to human Angiotensin Converting Enzyme 2 (ACE2) located on the cell surface. The protein has a cleavage site between the S1 and S2 subunits that is targeted by the human enzyme Furin, and it may also cause the development of a syncytium (cell fusion). Antibodies to S protein can prevent viral entry as well as target the virus for further immune action.

Target	SARS-CoV-2 Spike Protein
Research Area	Biosimilars
Clonality	Monoclonal
Reactivity	Virus
Host	Human
Recommended dilutions	Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Isotype	IgG1 Lambda
Form	Liquid
Purity	> 95%
Purification	Purified by Protein A or G.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Buffer	PBS, pH 7.4.
Concentration	1.93 mg/ml
Availability	Shipped within 1-3 working days.
Note	THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Directions for use	Centrifuge before opening to ensure complete recovery of vial contents.

Research Articles on SARS-CoV-2 Spike Protein

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