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SARS-CoV-2 Trimeric Spike Glycoprotein
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Catalogue No: abx620027
Price:
US$609.00
(Size: 100 µg)
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Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Trimeric Spike Glycoprotein is a recombinant protein expressed in Mammalian cells. The SARS-CoV-2 Spike Glycoprotein (S protein) is a viral protein that allows the entry of SARS-CoV-2 into Human cells. The protein forms trimers on the viral capsid and binds to human Angiotensin Converting Enzyme 2 (ACE2) located on the cell surface. The protein has a cleavage site between the Spike Protein and S2 subunits that is targeted by the human enzyme Furin, and it may also cause the development of a syncytium (cell fusion). Antibodies to S protein can prevent viral entry as well as target the virus for further immune action.
Research Articles on SARS-CoV-2 Trimeric Spike Glycoprotein
| Target | SARS-CoV-2 Trimeric Spike Glycoprotein |
| Research Area | Infection Immunity |
| Origin | Virus |
| Expression | Recombinant |
| Tested Applications | ELISA, WB, SDS-PAGE |
| Host | Mammalian cells |
| Recommended dilutions | Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Form | Lyophilized |
| Purity | > 90% (SDS-PAGE) |
| Reconstitution | Reconstitute in sterile water to produce a stock solution. |
| Storage | Store at 2-8°C for short-term storage. Store between -20°C and -80°C for up to one year. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P0DTC2 (UniProt, ExPASy) |
| UniProt Entry Name | SPIKE_SARS2 |
| Gene Symbol | S |
| NCBI Accession | YP_009724390 |
| Molecular Weight | Calculated MW: 140.15 kDa |
| Sequence Fragment | Gln14-Gln1208 |
| Tag | C-terminal His tag |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 5% Trehalose, 2% Mannitol. |
| Specificity | Recognizes SARS-CoV-2 Spike glycoprotein |
| Concentration | Prior to lyophilization: 1.52 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |