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SARS-CoV-2/COVID-19 Nucleocapsid Protein

Catalogue No: abx163973
Price: £200.00
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Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2/COVID-19) Nucleocapsid Protein is a recombinant protein expressed in E. coli.

The SARS-CoV-2 Nucleoprotein (also known as Nucleocapsid Protein or N Protein) is a protein that binds to the RNA in the viral particle. Changes to two amino acids in the nucleoprotein are thought to contribute to the virus’ ability to infect humans; this mutation allows the virus to reduce the binding capability of an HLA-C allele found in many Europeans. The nucleoprotein is the second most-common protein in SARS-CoV-2 targeted by the immune system, after the spike protein.

Target Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2/COVID-19) Nucleocapsid Protein
Origin Virus
Expression Recombinant
Tested Applications ELISA, SDS-PAGE, WB
Host E. coli
Recommended dilutions Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Form Liquid
Purity > 95% (SDS-PAGE)
Purification 0.2 µm filtered.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
NCBI Accession QHD43423.2
Sequence Fragment Met1-Ala419
Sequence MSDNGPQNQR NAPRITFGGP SDSTGSNQNG ERSGARSKQR RPQGLPNNTA SWFTALTQHG KEDLKFPRGQ GVPINTNSSP DDQIGYYRRA TRRIRGGDGK MKDLSPRWYF YYLGTGPEAG LPYGANKDGI IWVATEGALN TPKDHIGTRN PANNAAIVLQ LPQGTTLPKG FYAEGSRGGS QASSRSSSRS RNSSRNSTPG SSRGTSPARM AGNGGDAALA LLLLDRLNQL ESKMSGKGQQ QQGQTVTKKS AAEASKKPRQ KRTATKAYNV TQAFGRRGPE QTQGNFGDQE LIRQGTDYKH WPQIAQFAPS ASAFFGMSRI GMEVTPSGTW LTYTGAIKLD DKDPNFKDQV ILLNKHIDAY KTFPPTEPKK DKKKKADETQ ALPQRQKKQQ TVTLLPAADL DDFSKQLQQS MSSADSTQA
Tag N-terminal 6x His-tag.
Buffer 20 mM Tris-HCl, 300 mM NaCl, 10% glycerol, 1 mM EDTA, pH 8.0.
Endotoxin Level < 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on SARS-CoV-2/COVID-19 Nucleocapsid Protein

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