SARS-CoV-2 Nucleoprotein CTD Domain

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2/COVID-19) Nucleoprotein CTD Domain is a recombinant protein expressed in E. coli.

The SARS-CoV-2 Nucleoprotein (also known as Nucleocapsid Protein or N Protein) is a protein that binds to the RNA in the viral particle. Changes to two amino acids in the nucleoprotein are thought to contribute to the virus’ ability to infect humans; this mutation allows the virus to reduce the binding capability of an HLA-C allele found in many Europeans. The nucleoprotein is the second most-common protein in SARS-CoV-2 targeted by the immune system, after the spike protein.

Target	Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Nucleoprotein CTD Domain
Origin	Virus
Expression	Recombinant
Tested Applications	ELISA, WB, SDS-PAGE
Host	E. coli
Recommended dilutions	Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Form	Liquid
Purity	> 95% (SDS-PAGE)
Purification	0.2 µm filtered.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
NCBI Accession	QHD43423.2
Tag	N-terminal 6 His tag
Buffer	PBS, 2 M Urea, pH 7.4.
Endotoxin Level	< 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
Availability	Shipped within 7-12 working days.
Note	This product is for research use only.

Research Articles on Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Nucleoprotein CTD Domain

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