SARS-CoV-2 Spike Glycoprotein Antibody

Catalogue No: abx376478
Price: £240.00
(Size: 50 µg)
Reviews: 1 reviews
(1 reviews)

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SARS-CoV-2/COVID-19 Spike Glycoprotein Antibody is a chimaeric recombinant Monoclonal antibody expressed in CHO cells against SARS-CoV-2 Spike Glycoprotein, containing Mouse variable region and Human IgG1 Kappa constant region.

The SARS-CoV-2 Spike Protein (S protein) is a viral protein that allows the entry of SARS-CoV-2 into human cells. The protein forms trimers on the viral capsid and binds to human Angiotensin Converting Enzyme 2 (ACE2) located on the cell surface. The protein has a cleavage site between the S1 and S2 subunits that is targeted by the human enzyme Furin, and it may also cause the development of a syncytium (cell fusion). Antibodies to S protein can prevent viral entry as well as target the virus for further immune action.

Target Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Spike Glycoprotein
Clonality Monoclonal
Reactivity Virus
Origin Human
Expression Recombinant
Tested Applications ELISA, WB
Host Human, Mouse
Recommended dilutions ELISA: 1/5000 - 1/10000, WB: 1/1000 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant SARS-CoV-2 S1 protein.
Isotype IgG1 Kappa
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Buffer PBS, pH 7.5.
Concentration 2 mg/ml
Availability Shipped within 10-20 working days.
Note This product is for research use only.
Research Articles on Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Spike Glycoprotein

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