SARS-CoV-2 Spike Glycoprotein Antibody
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Catalogue No: abx243126
Price:
US$333.50
(Size: 50 µl)
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Datasheet SDS
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2/COVID-19) Spike Glycoprotein Antibody is a chimaeric recombinant antibody expressed in HEK293 cells for the detection of SARS-CoV-2/COVID-19 S Protein. This antibody contains Mouse scFv and C-terminal Human IgG1 Fc tag. The SARS-CoV-2 Spike Protein (S protein) is a viral protein that allows the entry of SARS-CoV-2 into human cells. The protein forms trimers on the viral capsid and binds to human Angiotensin Converting Enzyme 2 (ACE2) located on the cell surface. The protein has a cleavage site between the S1 and S2 subunits that is targeted by the human enzyme Furin, and it may also cause the development of a syncytium (cell fusion). Antibodies to S protein can prevent viral entry as well as target the virus for further immune action.
Research Articles on SARS-CoV-2 Spike Glycoprotein
| Target | SARS-CoV-2 Spike Glycoprotein |
| Research Area | Infection Immunity, Microbiology |
| Clonality | Monoclonal |
| Reactivity | Virus |
| Origin | Human |
| Expression | Recombinant |
| Tested Applications | ELISA |
| Host | Human, Mouse |
| Recommended dilutions | ELISA: 1/10000 - 1/50000, LF (GICA): 1/500 - 1/5000, Neutralization: 1/50 - 1/10000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant SARS-CoV-2 S protein (16-685 AA) expressed in Mammalian cells |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P0DTC2 (UniProt, ExPASy) |
| GeneID | 43740568 |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |