SARS-CoV-2 Spike Protein Antibody

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2/COVID-19) Spike Protein Antibody is a chimaeric recombinant Monoclonal Antibody against SARS-CoV-2/COVID-19 S Protein, containing Mouse variable region and Human IgG1 constant region.

The SARS-CoV-2 Spike Protein (S protein) is a viral protein that allows the entry of SARS-CoV-2 into human cells. The protein forms trimers on the viral capsid and binds to human Angiotensin Converting Enzyme 2 (ACE2) located on the cell surface. The protein has a cleavage site between the S1 and S2 subunits that is targeted by the human enzyme Furin, and it may also cause the development of a syncytium (cell fusion). Antibodies to S protein can prevent viral entry as well as target the virus for further immune action.

Target	Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Trimeric Spike 1 Protein
Clonality	Monoclonal
Clone	P560
Reactivity	Virus
Origin	Human
Expression	Recombinant
Tested Applications	ELISA, IF/ICC
Host	Human, Mouse
Recommended dilutions	ELISA: 1/5000 - 1/10000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant SARS-CoV-2 Spike RBD Protein
Isotype	IgG1
Form	Liquid
Purification	0.2 µm filtered.
Storage	Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Buffer	PBS.
Concentration	1 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.
Directions for use	Centrifuge before opening to ensure complete recovery of vial contents.

Research Articles on Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Trimeric Spike 1 Protein

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