Scavenger Receptor Class B Member 1 (SCARB1) Antibody

Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells. Probable receptor for HDL, located in particular region of the plasma membrane, called caveolae. Facilitates the flux of free and esterified cholesterol between the cell surface and extracellular donors and acceptors, such as HDL and to a lesser extent, apoB-containing lipoproteins and modified lipoproteins. Probably involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity. Receptor for hepatitis C virus glycoprotein E2. Binding between SCARB1 and E2 was found to be independent of the genotype of the viral isolate. Plays an important role in the uptake of HDL cholesteryl ester (By similarity).

Target	Scavenger Receptor Class B Member 1 (SCARB1)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 72-101 amino acids from the N-terminal region of human SCARB1.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q8WTV0 (UniProt, ExPASy)
UniProt Secondary AC	F8W8N0, Q14016, Q52LZ5, Q6KFX4
UniProt Entry Name	SCRB1_HUMAN
Gene Symbol	SCARB1
KEGG	hsa:949
String	9606.ENSP00000261693
Molecular Weight	Calculated MW: 60.9 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Pig SCARB1.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Scavenger Receptor Class B Member 1 (SCARB1)

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