Amiloride Sensitive Sodium Channel Subunit Alpha (SCNN1A) Antibody
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Catalogue No: abx034112
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US$326.25
(Size: 80 µl)
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Datasheet SDS
Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the alpha subunit, and mutations in this gene have been sociated with pseudohypoaldosteronism type 1 (PHA1), a rare salt wasting disease resulting from target organ unresponsiveness to mineralocorticoids.
Research Articles on Amiloride Sensitive Sodium Channel Subunit Alpha (SCNN1A)
| Target | Amiloride Sensitive Sodium Channel Subunit Alpha (SCNN1A) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, IF/ICC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/2000, IHC-P: 1/10 - 1/50, IF/ICC: 1/10 - 1/50, FCM: 1/25. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 365-391 amino acids from the Central region of human SCNN1A. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P37088 (UniProt, ExPASy) |
| UniProt Secondary AC | A5X2U9, B4E2Q5, C5HTZ0, O43271, Q6GSQ6, Q9UM64 |
| UniProt Entry Name | SCNNA_HUMAN |
| Gene Symbol | SCNN1A |
| KEGG | hsa:6337 |
| String | 9606.ENSP00000353292 |
| Molecular Weight | Calculated MW: 75.7 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |