Syndecan 1 (SDC1) Antibody
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Catalogue No: abx147270
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US$420.50
(Size: 100 µg)
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Datasheet SDS
Syndecan 1 (SDC1) Antibody is a Rabbit Polyclonal antibody for the detection of CD138. The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.
Research Articles on Syndecan 1 (SDC1)
| Target | Syndecan 1 (SDC1) |
| Research Area | Tumor Immunity, Infection Immunity, Immunodeficiency, Cancer |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | syndecan 1 |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P18827 (UniProt, ExPASy) |
| UniProt Secondary AC | D6W523, Q53QV0, Q546D3, Q96HB7 |
| UniProt Entry Name | SDC1_HUMAN |
| Gene Symbol | SDC1 |
| GeneID | 6382 |
| OMIM | 186355 |
| HGNC | 10658 |
| KEGG | hsa:6382 |
| Ensembl | ENSG00000115884 |
| String | 9606.ENSP00000370542 |
| Molecular Weight | Observed MW: 85-120 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |