Syndecan 1 (SDC1) Antibody

SDC1 Antibody is a Rabbit Polyclonal antibody against SDC1. The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein. [provided by RefSeq, Jul 2008].

Target	Syndecan 1 (SDC1)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 25-240 of human CD138/Syndecan-1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P18827 (UniProt, ExPASy)
UniProt Secondary AC	D6W523, Q53QV0, Q546D3, Q96HB7
UniProt Entry Name	SDC1_HUMAN
Gene Symbol	SDC1
GeneID	6382
NCBI Accession	NP_002988.4
KEGG	hsa:6382
String	9606.ENSP00000370542
Molecular Weight	Calculated MW: 32 kDa Observed MW: 32/96 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Syndecan 1 (SDC1)

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