Succinate Dehydrogenase Complex Subunit D (SDHD) Antibody
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Catalogue No: abx026621
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US$326.25
(Size: 80 µl)
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Datasheet SDS
Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The subunit D protein is one of two integral membrane proteins anchoring the complex to the matrix side of the membrane. Mutations in SDHD have been linked to hereditary paraganglioma.
Research Articles on Succinate Dehydrogenase Complex Subunit D (SDHD)
| Target | Succinate Dehydrogenase Complex Subunit D (SDHD) |
| Research Area | Enzymes and Kinases |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, IF/ICC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50, IF/ICC: 1/10 - 1/50, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 13-42 amino acids from the N-terminal region of human SDHD. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | O14521 (UniProt, ExPASy) |
| UniProt Secondary AC | A6ND90, B3KQQ8, E9PIC0, E9PIG3, E9PQI9, Q53XW5, Q6IRW2 |
| UniProt Entry Name | DHSD_HUMAN |
| Gene Symbol | SDHD |
| KEGG | hsa:6392 |
| String | 9606.ENSP00000364699 |
| Molecular Weight | Calculated MW: 17 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |