Selenocysteine Insertion Sequence-Binding Protein 2 (SECISBP2) Antibody

SECISBP2 Antibody is a Rabbit Polyclonal antibody against SECISBP2. The incorporation of selenocysteine into a protein requires the concerted action of an mRNA element called a sec insertion sequence (SECIS), a selenocysteine-specific translation elongation factor and a SECIS binding protein. With these elements in place, a UGA codon can be decoded as selenocysteine. The gene described in this record encodes a nuclear protein that functions as a SECIS binding protein. Mutations in this gene have been associated with a reduction in activity of a specific thyroxine deiodinase, a selenocysteine-containing enzyme, and abnormal thyroid hormone metabolism. Alternate splicing results in multiple transcript variants.

Target	Selenocysteine Insertion Sequence-Binding Protein 2 (SECISBP2)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/100 - 1/500, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 585-854 of human SECISBP2.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q96T21 (UniProt, ExPASy)
UniProt Secondary AC	F8W892, Q5HYY1, Q7L1Z0, Q8IYC0, Q9H0A1
UniProt Entry Name	SEBP2_HUMAN
Gene Symbol	SECISBP2
GeneID	79048
NCBI Accession	NP_076982.3
KEGG	hsa:79048
String	9606.ENSP00000364965
Molecular Weight	Calculated MW: 95 kDa Observed MW: 110 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Selenocysteine Insertion Sequence-Binding Protein 2 (SECISBP2)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue