E-Selectin / CD62E (SELE) Antibody

SELE Antibody is a Rabbit Polyclonal antibody against SELE. The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis. [provided by RefSeq].

Target	E-Selectin / CD62E (SELE)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 22-230 of human SELE.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P16581 (UniProt, ExPASy)
UniProt Secondary AC	A2RRD6, P16111
UniProt Entry Name	LYAM2_HUMAN
Gene Symbol	SELE
GeneID	6401
NCBI Accession	NP_000441.2
KEGG	hsa:6401
String	9606.ENSP00000331736
Molecular Weight	Calculated MW: 67 kDa Observed MW: 67 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on E-Selectin / CD62E (SELE)

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