Semaphorin 7A (SEMA7A) Antibody
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Catalogue No: abx034989
Price:
US$326.25
(Size: 80 µl)
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Datasheet SDS
Plays an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. Promotes formation of focal adhesion complexes, activation of the protein kinase PTK2/FAK1 and subsequent phosphorylation of MAPK1 and MAPK3. Promotes production of proinflammatory cytokines by monocytes and macrophages. Plays an important role in modulating inflammation and T-cell-mediated immune responses. Promotes axon growth in the embryonic olfactory bulb. Promotes attachment, spreading and dendrite outgrowth in melanocytes.
Research Articles on Semaphorin 7A (SEMA7A)
| Target | Semaphorin 7A (SEMA7A) |
| Research Area | Signal Transduction, Cellular Differentiation and Adhesion, Tumor Immunity, Infection Immunity, Autoimmunity, Cancer |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 178-202 amino acids from the N-terminal region of human SEMA7A. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | O75326 (UniProt, ExPASy) |
| UniProt Secondary AC | B4DDP7, F5H1S0, Q1XE81, Q1XE82, Q1XE83, Q1XE84, Q3MIY5 |
| UniProt Entry Name | SEM7A_HUMAN |
| Gene Symbol | SEMA7A |
| NCBI Accession | NP_001139501.1 NP_001139502.1 NP_003603.1 |
| KEGG | hsa:8482 |
| String | 9606.ENSP00000261918 |
| Molecular Weight | Calculated MW: 74.8 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |