Selenoprotein P / SEPP1 (SELENOP) Antibody
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Catalogue No: abx029199
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US$326.25
(Size: 80 µl)
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Datasheet SDS
This gene encodes a selenoprotein containing multiple selenocysteine (Sec) residues, which are encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This selenoprotein is an extracellular glycoprotein, and is unusual in that it contains 10 Sec residues per polypeptide. It is a heparin-binding protein that appears to be associated with endothelial cells, and has been implicated to function as an antioxidant in the extracellular space. Several transcript variants, encoding either the same or different isoform, have been found for this gene.
Research Articles on Selenoprotein P / SEPP1 (SELENOP)
| Target | Selenoprotein P / SEPP1 (SELENOP) |
| Research Area | Metabolism, Infection Immunity |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/2000, FCM: 1/25. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 233-262 amino acids from the Central region of Human SEPP1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P49908 (UniProt, ExPASy) |
| UniProt Secondary AC | Q6PD59, Q6PI43, Q6PI87, Q6PJF9 |
| UniProt Entry Name | SEPP1_HUMAN |
| Gene Symbol | SELENOP |
| GeneID | 6414 |
| OMIM | 601484 |
| NCBI Accession | NP_001078955.1 NP_005401.3 |
| KEGG | hsa:6414 |
| String | 9606.ENSP00000420939 |
| Molecular Weight | Calculated MW: 43 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Concentration | 0.4 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |