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Sequestosome 1 (SQSTM1) Antibody
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Catalogue No: abx016000
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US$427.75
(Size: 100 µl)
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Datasheet SDS
This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway.The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals.Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene.Mutations in this gene result in sporadic and familial Paget disease of bone.
Research Articles on Sequestosome 1 (SQSTM1)
| Target | Sequestosome 1 (SQSTM1) |
| Research Area | Biomarkers |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, FCM |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human SQSTM1 (AA: 232-356) expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Purified from ascites by Protein G chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q13501 (UniProt, ExPASy) |
| UniProt Secondary AC | A6NFN7, B2R661, B3KUW5, Q13446, Q9BUV7, Q9BVS6, Q9UEU1 |
| UniProt Entry Name | SQSTM_HUMAN |
| Gene Symbol | SQSTM1 |
| GeneID | 8878 |
| OMIM | 167250 |
| HGNC | 11280 |
| KEGG | hsa:8878 |
| Ensembl | ENSG00000161011 |
| String | 9606.ENSP00000374455 |
| Molecular Weight | 47.7 kDa |
| Buffer | PBS, containing 0.05% sodium azide. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |