Serine/Threonine-Protein Kinase Sgk1 (SGK1) Antibody

Serine/Threonine-Protein Kinase Sgk1 (SGK1) Antibody is a Rabbit Polyclonal antibody for the detection of SGK1.

This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Target	Serine/Threonine-Protein Kinase Sgk1 (SGK1)
Research Area	Signal Transduction
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	serum/glucocorticoid regulated kinase 1
Isotype	IgG
Form	Liquid
Purity	≥ 95% (SDS-PAGE)
Purification	Purified by immunogen affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Shelf Life	12 months.
UniProt Primary AC	O00141 (UniProt, ExPASy)
UniProt Entry Name	SGK1_HUMAN
Gene Symbol	SGK1
GeneID	6446
OMIM	602958
HGNC	10810
KEGG	hsa:6446
Ensembl	ENSG00000118515
String	9606.ENSP00000356832
Molecular Weight	Observed MW: 60 kDa
Buffer	PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration	2 mg/ml
Availability	Shipped within 5-12 working days.
Note	THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Research Articles on Serine/Threonine-Protein Kinase Sgk1 (SGK1)

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