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Antithrombin-III (SERPINC1) Antibody

Catalogue No: abx001325
Price: £120.00
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Antithrombin-III (SERPINC1) Antibody Antithrombin-III (SERPINC1) Antibody

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SERPINC1 Antibody is a Rabbit Polyclonal antibody against SERPINC1. SERPINC1, also named Antithrombin III or Antithrombin, is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.

Target SERPINC1
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human SERPINC1.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P01008 (UniProt, ExPASy)
UniProt Entry Name ANT3_HUMAN
Gene Symbol SERPINC1
GeneID 462
KEGG hsa:462
String 9606.ENSP00000356671
Molecular Weight Calculated MW: 52 kDa
Observed MW: 50 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Antithrombin-III (SERPINC1) Antibody

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