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Pigment Epithelium-Derived Factor / PEDF (SERPINF1) Antibody
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Catalogue No: abx001406
Price:
US$348.00
(Size: 60 µl)
Orders to United States ship from United States
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Pigment Epithelium-Derived Factor / PEDF (SERPINF1) Antibody is a Rabbit Polyclonal antibody against SERPINF1. Pigment epithelium-derived growth factor (PEDF), also known as EPC-1 (early population doubling level cDNA-1), is a glycoprotein found naturally in the normal eye. PEDF has reported neuroprotective and differentiation properties and is secreted in abundance by retinal pigment epithelium cells. It belongs to the serine protease inhibitor (Serpin) superfamily and has been reported to inhibit angiogenesis and proliferation of several cell types. The pooling of PEDF within the interphotoreceptor matrix places this molecule in a prime physical location to affect the underlying neural retina. Additionally, PEDF induces neuronal differentiation and promotes survival of neurons of the central nervous system from degeneration caused by serum withdrawal or glutamate cytotoxicity.
Research Articles on Pigment Epithelium-Derived Factor / PEDF (SERPINF1)
| Target | Pigment Epithelium-Derived Factor / PEDF (SERPINF1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic peptide corresponding to human PEDF/SERPINF1 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P36955 (UniProt, ExPASy) |
| UniProt Secondary AC | F1T092, Q13236, Q2TU83, Q96CT1, Q96R01, Q9BWA4 |
| UniProt Entry Name | PEDF_HUMAN |
| Gene Symbol | SERPINF1 |
| GeneID | 5176 |
| OMIM | 172860 |
| NCBI Accession | NP_002606.3 |
| HGNC | 8824 |
| KEGG | hsa:5176 |
| Ensembl | ENSG00000132386 |
| String | 9606.ENSP00000254722 |
| Molecular Weight | Calculated MW: 46 kDa Observed MW: 46 kDa |
| Buffer | PBS, pH 7.3, containing 0.01% thiomersal, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
