SESN3 Antibody is a Rabbit Polyclonal antibody against SESN3. This gene encodes a member of the sestrin family of stress-induced proteins. The encoded protein reduces the levels of intracellular reactive oxygen species induced by activated Ras downstream of RAC-alpha serine/threonine-protein kinase (Akt) and FoxO transcription factor. The protein is required for normal regulation of blood glucose, insulin resistance and plays a role in lipid storage in obesity. Alternative splicing results in multiple transcript variants.

Target	Sestrin 3 (SESN3)
Research Area	Neuroscience
Clonality	Polyclonal
Reactivity	Human
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/200 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein corresponding to human SESN3
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Shelf Life	12 months.
UniProt Primary AC	P58005 (UniProt, ExPASy)
UniProt Secondary AC	B7Z7P9, Q96AD1
UniProt Entry Name	SESN3_HUMAN
Gene Symbol	SESN3
GeneID	143686
NCBI Accession	NP_653266.2
KEGG	hsa:143686
String	9606.ENSP00000441927
Molecular Weight	Calculated MW: 36 kDa/41 kDa/57 kDa Observed MW: 50 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	1 mg/ml
Availability	Shipped within 5-10 working days.
Note	THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Research Articles on Sestrin 3 (SESN3)

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