Sestrin 3 (SESN3) Antibody

SESN3 Antibody is a Rabbit Polyclonal antibody against SESN3. This gene encodes a member of the sestrin family of stress-induced proteins. The encoded protein reduces the levels of intracellular reactive oxygen species induced by activated Ras downstream of RAC-alpha serine/threonine-protein kinase (Akt) and FoxO transcription factor. The protein is required for normal regulation of blood glucose, insulin resistance and plays a role in lipid storage in obesity. Alternative splicing results in multiple transcript variants.

Target	Sestrin 3 (SESN3)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/200 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-310 of human SESN3.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P58005 (UniProt, ExPASy)
UniProt Secondary AC	B7Z7P9, Q96AD1
UniProt Entry Name	SESN3_HUMAN
Gene Symbol	SESN3
GeneID	143686
NCBI Accession	NP_653266.2
KEGG	hsa:143686
String	9606.ENSP00000441927
Molecular Weight	Calculated MW: 57 kDa Observed MW: 50 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Sestrin 3 (SESN3)

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