SET Domain Containing Protein 2 (SETD2) Antibody

Catalogue No: abx002294
Price: £120.00
(Size: 20 µl)
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SETD2 Antibody is a Rabbit Polyclonal antibody against SETD2. Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II.

Target SETD2
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 803-1103 of human SETD2.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q9BYW2 (UniProt, ExPASy)
UniProt Entry Name SETD2_HUMAN
Gene Symbol SETD2
GeneID 29072
String 9606.ENSP00000386759
Molecular Weight Calculated MW: 175 kDa, 192 kDa, 287 kDa
Observed MW: 300 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration 1.23 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on SET Domain Containing Protein 2 (SETD2) Antibody

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