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SET Domain Bifurcated 1 (SETDB1) Antibody
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Catalogue No: abx025881
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US$326.25
(Size: 80 µl)
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Datasheet SDS
The SET domain is a highly conserved, approximately 150-amino acid motif implicated in the modulation of chromatin structure. It was originally identified as part of a larger conserved region present in the Drosophila Trithorax protein and was subsequently identified in the Drosophila Su (var) 3-9 and 'Enhancer of zeste' proteins, from which the acronym SET is derived. Studies have suggested that the SET domain may be a signature of proteins that modulate transcriptionally active or repressed chromatin states through chromatin remodeling activities.
Research Articles on SET Domain Bifurcated 1 (SETDB1)
| Target | SET Domain Bifurcated 1 (SETDB1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 1193-1225 amino acids from the C-terminal region of human SETDB1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q15047 (UniProt, ExPASy) |
| UniProt Secondary AC | A6NEW2, Q5SZD8, Q5SZD9, Q5SZE0, Q5SZE7, Q96GM9 |
| UniProt Entry Name | SETB1_HUMAN |
| KEGG | hsa:9869 |
| String | 9606.ENSP00000271640 |
| Molecular Weight | Calculated MW: 143 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Zebrafish and Xenopus SETDB1. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |