Histone-Lysine N-Methyltransferase SETMAR (SETMAR) Antibody

SETMAR Antibody is a Rabbit Polyclonal antibody against SETMAR. This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants.

Target	Histone-Lysine N-Methyltransferase SETMAR (SETMAR)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	IHC
Host	Rabbit
Recommended dilutions	IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 20-300 of human SETMAR.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q53H47 (UniProt, ExPASy)
UniProt Secondary AC	B4DY74, E7EN68, Q13579, Q1G668, Q96F41
UniProt Entry Name	SETMR_HUMAN
Gene Symbol	SETMAR
GeneID	6419
NCBI Accession	NP_006506.3
KEGG	hsa:6419
String	9606.ENSP00000373354
Molecular Weight	Calculated MW: 78 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Histone-Lysine N-Methyltransferase SETMAR (SETMAR)

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