Splicing Factor Proline And Glutamine Rich (SFPQ) Antibody

Catalogue No: abx000914
Price: £120.00
(Size: 20 µl)
Reviews: 0 reviews
(0 reviews)

Click on the image to see the image legend

Available Options

* Size:

SFPQ Antibody is a Rabbit Polyclonal antibody against SFPQ. SFPQ, also named PSF, encodes a nuclear factor implicated in the splicing and regulation of gene expression. SFPQ probably forms a heteromer with NONO and participates in DNA pairing and DNA break repair program. Very recently SFPQ was identified as a downstream target of tau, complete nuclear depletion and cytoplasmic accumulation of SFPQ were shown in the neurons and astrocytes of brains with Alzheimer's disease (AD), more strikingly, reduced SFPQ levels may progress together with tau pathology, these observation strongly suggests the important role of SFPQ pathology in neurodegenerative diseases including AD. SFPQ protein may appears as 47 kDa, 52 kDa or 100 kDa molecules in various cell types. Catalog# 15585-1-AP is a rabbit polyclonal antibody raised against the N-terminal of human SFPQ.

Target SFPQ
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC, IF/ICC, IP
Host Rabbit
Recommended dilutions WB: 1/500 - 1/1000, IHC: 1/50 - 1/100, IF/ICC: 1/50 - 1/100, IP: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein of human SFPQ.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P23246 (UniProt, ExPASy)
UniProt Secondary AC P30808, Q5SZ71
UniProt Entry Name SFPQ_HUMAN
Gene Symbol SFPQ
GeneID 6421
KEGG hsa:6421
String 9606.ENSP00000349748
Molecular Weight Calculated MW: 72 kDa, 76 kDa
Observed MW: 115 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 0.5 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on SFPQ

Write a review

Your Name
Your Email Address
Your Review

Note: HTML is not translated!

Rating Bad Good

(Click to show)